Hands-on GC and GC-MS advanced injection
- Duration: 2 days for live courses
- Experience level: Advanced
- Delivery methods: Face-to-face | Offsite training & consultancy | Onsite training & consultancy | Tailored training |
- Type of course: Universal
- Applicable to manufacturer(s): Agilent | GERSTEL | GL Sciences | PerkinElmer | Scion | Shimadzu | Thermo |
- CPD Approved: Approved
- Scheduled course price: £1,250.00 + TAX per delegate
- Course discounts: RSC CAMS HEaTED Cambridge Network members receive a discount on this course
Your Hands-on approach to advanced GC and GC-MS sample introduction techniques
Combine the theory of advanced GC and GC-MS injection techniques with practical laboratory-based exercises in this 2-day Hands-on advanced training approved by the Royal Society of Chemistry (RSC) for the purposes of Continuing Professional Development (CPD). Designed for professionals, students and scientists who are experienced GC users, this course bridges the gap between understanding advanced sample introduction principles and confidently applying them in the laboratory.
Using practical laboratory exercises, you will configure and optimise programmable temperature vaporisers (PTVs), multi-mode inlets (MMIs), split and splitless methods, large volume injection (LVI) techniques, thermal desorption workflows, pyrolysis methods, and advanced inlet configurations. This advanced course will enhance your knowledge of GC and GC-MS, taking it to an advanced level.
Why should I join?
On completion, you will have both the theoretical and practical experience required to confidently optimise advanced GC and GC-MS injection techniques, giving you:
- Strong theoretical and practical knowledge of advanced sample introduction in GC and GC-MS systems
- Hands-on experience configuring and operating PTV and MMI inlets
- Understanding of hot and cold injection techniques and when each should be applied
- Confidence using large volume injection to improve detection limits and sample throughput
- Practical knowledge of thermal desorption, thermal extraction, and pyrolysis techniques
- Improved understanding of inlet liners, septa, packing materials, and deactivation technologies
- Troubleshooting skills to identify and resolve discrimination, activity, contamination, and sensitivity issues
- A structured approach to advanced method development for difficult, trace, thermally labile and high molecular weight analytes
What would I learn?
A practical course combining advanced injection theory with laboratory-based exercises, you will learn:
- The fundamentals of GC and GC-MS sample introduction and analyte transfer
- The operation and capabilities of Programmable Temperature Vaporisers (PTVs) and Multi-Mode Inlets (MMIs)
- The differences between hot and cold injection techniques
- How to minimise thermal degradation and mass discrimination during sample introduction
- Split and splitless injection optimisation, including solvent focusing and cold trapping effects
- Large Volume Injection (LVI) techniques including Rapid LVI (RLVI), Speed Controlled LVI (SCLVI) and Multiple Injection LVI (MILVI)
- Selection and optimisation of liners, packing materials and inlet components
- Practical maintenance, troubleshooting, and performance optimisation of advanced inlet systems
What knowledge will I gain?
- Understand the complete workflow involved in advanced GC and GC-MS sample introduction
- Be confident discussing the theory, operation, and applications of PTV and MMI systems
- Understand how injection parameters influence sensitivity, reproducibility, and chromatographic performance
- Confidently select appropriate injection techniques for trace, thermally labile, active, and high molecular weight analytes
- Optimise split ratios, splitless times, inlet temperatures, and transfer conditions
- Understand solvent effects, cold trapping and analyte focusing mechanisms
- Select and maintain liners, septa, ferrules, and packing materials to maximise analytical performance
- Develop and optimise large volume injection methods for improved sensitivity and lower detection limits
- Recognise common causes of carryover, contamination, discrimination, and analyte loss
- Apply effective troubleshooting strategies to improve method robustness and reliability
Is this course for me?
This Hands-on training course is designed for anyone who requires both a theoretical and practical understanding of advanced GC and GC-MS injection techniques, including:
- Analysts and technicians performing GC and GC-MS analysis
- Scientists responsible for trace-level analysis and method development
- Laboratory managers seeking improved analytical performance and productivity
- Service engineers maintaining advanced chromatographic systems
- Data analysts and technical specialists investigating chromatographic performance issues
- Sales, marketing and commercial professionals working with chromatography instrumentation and consumables
If advanced injection techniques touches your work in any way, this practical course delivered by industry experts will equip you with the skills needed to confidently develop, optimise, and troubleshoot advanced GC and GC-MS injection methods in your laboratory.
What's next?
Feedback from previous attendees
“[I enjoyed the] hands-on practical content.” delegate from an equipment supplier (March 2019).
“[I enjoyed] experimenting in the lab.” Melanie Schumacher, Technical Specialist, Natural Resources Wales (tailored training, January 2019).
“Very good level. Definitely I’ll recommend it! (I enjoyed) the discussions with Diane, her experience is impressive.” Andrea Rangel, Research Technologist, Nova Chemicals, Canada (September 2018).
“Good use of lecture time translating into laboratory exercises to illustrate the point fully.” International analytical sales support from an instrument manufacturer (February 2013).
“Very good content and course material, and allowed time for questions and comments, and good mix between class and hands on.” Senior analyst from an instrument manufacturer (February 2013).
“I learned a lot of little things that can really make a difference but I never thought about.” Claudia Moeckel, Environmental Chemist, attended the Hands-on PTV course (November 2011).
